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Collins McNicholas

Job Title: Spectroscopic Scientist

Location: South East UK

 

Role Responsibilities:

 

Role Description

We are currently recruiting for an enthusiastic and innovative scientist in the field of Solid State Chemistry and Characterisation in a drug product development functional area. This is an exciting opportunity based in the South East of the UK. The opportunity is for a graduate, ideally with a minimum 5 year’s relevant industrial experience.  Alternatively, a recent, relevant PhD will also be considered.

The purpose of this role is to utilize a broad range of spectroscopic techniques to characterize and monitor interactions between APIs and excipients within drug product formulations to build key information that will be used to optimize proposed drug product formulations

 

Main Duties and Responsibilities:

  • Excellent working knowledge of vibrational spectroscopic techniques, coupled with an understanding of their application in the analysis of pharmaceutically related materials.
  • Experience of using vibrational spectroscopy to understand and monitor interactions between API and excipients within a drug product would be considered advantageous.
  • Able to independently operate both infrared and Raman instrumentation, and demonstrate an awareness of the advantages and disadvantages of the respective techniques.
  • Demonstrate familiarity with the application of vibrational spectroscopy for quantitative analysis, including the development of calibration curves and the calculation of associated errors.
  • A good understanding of multivariate data analysis techniques is desirable.
  • The ability to work independently to use available resources such as online databases, look-up tables and literature to assist and enable spectral interpretation and assignment.
  • To interpret scientific data to derive clear conclusions and influence the development of quality drug products.
  • To communicate effectively to the project team and present data at team meetings.
  • To maintain high quality documentation of all activities in electronic notebooks and reports as required.
  • Maintain awareness of technical advances spectroscopic techniques to develop innovative and novel solutions with sound scientific rationale.

Experience and Qualifications

Degree in a scientific discipline like Chemical Engineering, Chemistry, Life Sciences or Biology with a minimum of 5 years relevant industrial experience.  Alternatively, a recent, relevant PhD will also be considered.

  • Strong written and verbal communication skills.
    Appropriate relevant experience of solid state chemistry and characterization in a development laboratory within a group organization.
  • Excellent working knowledge of vibrational spectroscopic techniques and an understanding of their application in the analysis of pharmaceutically related materials. Familiar with, and able to independently operate NIR, infrared and Raman instrumentation.
  • Demonstrate an awareness of the advantages and disadvantages of the different vibrational spectroscopic techniques. A good understanding of multivariate data analysis techniques is desirable. Expected to work with a high degree of autonomy, collect and interpret data efficiently and effectively in keeping with a ‘right first time’ approach.
  • Ability to take ownership, problem solve, and drive resolution of situations.
  • Ability to work using fully electronic media, including MS Office.
  • Ability to communicate clearly in written and orally and form strong working relationships with colleagues.
  • Ability to work in a lab environment with some supervision and be capable of developing solutions to problems as part of a team.
  • Willing to operate in a flexible manner and able to reuse both internal and external experiences and incorporate them into relevant improvements. Ability to switch priorities at short notice is desired.
  • Good team player, organised, accurate, have strong documentation skills.
  • Passionate about quality and client service.
  • Good understanding of requirements for working in a GLP environment.

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