We have a new opportunity for Neurovascular Postdoctoral Researcher with our client based in Dublin.
Salary & Benefits: Competitive package including pension, private health insurance, income protection, 25 days annual leave (plus additional company days), flexible working, hybrid options, and strong career development support.
Role Overview
An exciting opportunity for two Postdoctoral Research Scientists to join a collaborative, multidisciplinary research team working on the project “Cell Therapy Platform: Unlocking Life-Changing Treatments for Neonatal Brain Injury.”
The role focuses on developing a dual-cell therapy to treat neonatal hypoxia-associated brain injury, one of the leading causes of infant mortality and long-term neurological disorders globally.
Key Responsibilities
- Design and optimize in vitro hypoxia models of neonatal brain injury.
- Conduct proteomic and transcriptomic analyses (RNA-seq) to explore mechanisms of action.
- Integrate multi-omics data to identify therapeutic pathways and biomarkers.
- Define and validate critical quality attributes (CQAs) for MSCs and ECFCs.
- Develop and implement potency and release assays ensuring product consistency and compliance.
- Collaborate with GMP, regulatory, and clinical teams to support downstream activities.
- Lead data analysis, reporting, and manuscript preparation.
- Present findings at internal meetings, conferences, and consortium events.
- Contribute to project milestones, documentation, and regulatory submissions.
Essential Criteria
- PhD in Neuroscience, Cell Therapy, Regenerative Medicine, or a related field, with 3+ years postdoctoral experience.
- Proven experience in vitro/in vivo models of hypoxia or neurovascular injury.
- Expertise in cell biology, particularly with MSCs and ECFCs.
- Hands-on experience with omics technologies and data integration.
- Strong understanding of CQAs, potency assays, and ATMP release criteria.
- Analytical ability to manage and interpret complex biological datasets.
- Demonstrated project management skills and ability to meet research milestones.
- Excellent communication, writing, and presentation skills; experience mentoring others is an advantage.
For further details on this opportunity, please reach out to Gillian Nicholson to gillian.nicholson@collinsmcnicholas.ie